Folate and vitamin B12 status in schizophrenic patients
نویسندگان
چکیده
BACKGROUND This study aimed to determine red blood cell (RBC) and serum folate and vitamin B12 levels as well as their intake in schizophrenic patients. METHODS The folate and cobalamin status of 60 schizophrenic patients (15-55 years) was compared to 60 matched healthy controls using Radio Isotope Dilution Assay (RIDA). RESULTS Serum and RBC folate in schizophrenic patients was significantly lower than the control group. Mean serum cobalamin levels in the schizophrenic group were higher than controls. CONCLUSIONS This study showed that folate deficiency is common in schizophrenic patients; therefore, it is important to pay attention to folate levels in these patients.
منابع مشابه
Short Communication Folate and vitamin B12 status in schizophrenic patients
BACKGROUND: This study aimed to determine red blood cell (RBC) and serum folate and vitamin B12 levels as well as their intake in schizophrenic patients. METHODS: The folate and cobalamin status of 60 schizophrenic patients (15-55 years) was compared to 60 matched healthy controls using Radio Isotope Dilution Assay (RIDA). RESULTS: Serum and RBC folate in schizophrenic patients was significantl...
متن کاملSerum homocysteine, Vitamin B12 and folate Levels in Patients With Ischemic Cerebrovasculare disease
Monshi Karimi AR1, Mohtadi-nia J2, Farhodi M3 1. M.Sc Student of nutritional sciences, Faculty of Health, Tabriz University of Medical Sciences 2. Associated professor, Department of Nutritional, Faculty of Health, Tabriz University of Medical Sciences 3. Assistant professor, Department of Internal, Faculty of medicine, Tabriz University of Medical Sciences Abstract Background: Isc...
متن کاملSerum Levels of Homocysteine, Vitamin B12, and Folic Acid in Patients with Alzheimer’s Disease
Background: Alzheimer's disease is the most common form of dementia in the elderly. Serum levels of homocysteine have been related to increased cortical and hippocampal atrophy. We aimed to determine the serum levels of homocysteine, folate, and vitamin B12 in patients with Alzheimer's disease. Methods: Blood levels of homocysteine and its biological determinants, folate, and vitamin B12 were m...
متن کاملرابطه مقادیر فولات، ویتامین ب12 و هموسیستئین تام پلاسما با هیپرمتیلاسیون ژن رتینوئیک اسید رسپتور- بتا2 وابسته به سن در مبتلایان به سرطان پستان
Background & Objectives: The repression of retinoic acid receptor-β2 (RARβ2) expression is a concerning aspect of breast cancer, which is often induced by hypermethylation at promoter of the gene. We aimed to explore the correlation of plasma folate, vitamin B12 and total homocysteine (tHcy) levels with hypermethylation status of RARβ2 gene among Iranian breast cancer patients. Methods: The...
متن کاملDoes Short-Term Low-Dose Methotrexate Treatment Affect Homocysteine Blood Level in Patients with Psoriasis?
Background: An elevated homocysteine level is an independent risk factor for cardiovascular disorders. Psoriatic patients have an increased risk of cardiovascular diseases; In addition, hyperhomocysteinemia is a complication of methotrexate treatment. We undertook a study to evaluate the plasma levels of homocysteine, vitamin B12 and folate in patients with psoriasis before and after short-term...
متن کامل